Johns Hopkins Clinical Research Study

A pilot study to investigate filiation between primary and secondary lesions in acne patients

IRB Number: NA_00074888
Principal Investigator: Chien, Anna

Study Description:


The main goal of this study is to describe and document the link between acne spots and acne scars. The study also aims to evaluate the effect of Epiduo® gel compared to placebo on the prevention of acne scars and/or the treatment of pre-existing acne scars

Epiduo® gel is a combination of Adapalene 0.1% and benzoyl peroxide 2.5%. Adapalene is made from vitamin A and can help to control acne by decreasing the number of plugged skin pores. Recent studies also suggest that vitamin A derivatives like Adapalene may help the skin to produce a group of proteins known as collagen. Collagen may help improve the appearance of acne scars.

People with active, moderate acne on the face with scarring may join.

Your participation in this study may require up to 28 on-site visits over 7 months. 



Eligibility Criteria:

People with active, moderate acne on the face with scarring may join.

You may qualify if you:

-are age 18-35

-have indented facial acne scars

-and have active acne bumps on the face

Recruitment Contact Name:Eugene Balagula
Contact Phone:410-502-SKIN
Contact E-Mail: ctrep@jhmi.edu

Location of Study Visits:

  • Johns Hopkins Hospital East Baltimore Campus

Study will provide compensation: Yes


  • Acne Vulgaris
  • Inflammation
  • Retinoids