Johns Hopkins Clinical Research Study

Effects of Antibiotics and Acne on the Skin Microbiome

IRB Number: NA_00049124
Principal Investigator: Garza, Luis

Study Description:

This research is being done to study how oral antibiotics affect the bacteria in acne skin bumps.  

Many people with acne have different types of skin bumps.  One possible reason why some people have red and swollen acne is because of a bacterial infection inside the skin.  Oral antibiotics like Minocycline are approved by the Food and Drug Administration (FDA) and have been used successfully to treat red and inflamed acne.  In this study, we will examine skin samples taken from acne skin bumps before, during, and after the use of Minocycline.  The skin samples will be brought to our laboratory and we will look for different kinds of bacteria using specialized laboratory techniques.  After the study is over we hope to have a better understanding of bacteria in acne skin bumps so that we may develop better treatments for people with acne in the future.


Eligibility Criteria:

People with facial acne and who have not used oral, injected or topical antibiotics for at least one year prior to the start of this study may join.

Recruitment Contact Name:Dr. Luis Garza
Contact Phone:410-502-7546
Contact E-Mail: ctrep@jhmi.edu

Location of Study Visits:

  • Johns Hopkins Hospital East Baltimore Campus

Study will provide compensation: Yes


  • Acne Vulgaris
  • Minocycline
  • Skin
  • Skin Diseases
  • Skin Diseases, Bacterial
  • Face
  • Tetracyclines